Scenarios wanted! Please add your favorites! [Click on "Easy Edit", above]

Information about each scenario can include, but need not be limited to:

• the case
  
• the PICO'd question
  
• type of question/preferred study design
• suggested search strategies
• teaching tips

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Case: Based on outcome, cases averted, pregnancy loss, what is the most cost effective screening strategy for prenatal diagnosis of Down's syndrome?

SEARCH Strategy: prenatal diagnosis AND downs syndrome AND cost benefit
limit to english, and years desired

TEACHING Tips: prenatal screening doesn't map appropriately. must find correct term for cost effectiveness

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I found a nice fresh PICO scenario yesterday, when an OB/GYN asked me to do this search:

“What is the optimum timing of prophylactic antibiotics for cesareans—should they be given before the incision, or after clamping the cord?”

In addition to several RCT’s, there’s a 2008 meta-analysis:
Costantine MM, et al.
Timing of perioperative antibiotics for cesarean delivery: a metaanalysis.
Am J Obstet Gynecol. 2008 Sep;199(3):301.e1-6.
PMID: 18771991.

…as well as a 2009 systematic review:
Tita AT, et al.
Emerging concepts in antibiotic prophylaxis for cesarean delivery: a systematic review.
Obstet Gynecol. 2009 Mar;113(3):675-82. Review. PMID: 19300334.

It’s a textbook PICO exercise. Just thought I’d pass it along. From Jeannine Gluck, Eastern Connecticut Health network